The weather models are predicting varying amounts of snowfall for the region, anywhere from 1-6" across the viewing area from south to north.
The first map below shows the NAM weather model, and you can see it's putting out the heaviest amounts with a prediction of 3-6" across much of southern Indiana, and along and north of I-64. Areas to the south on this map are in the 1-4" range. This model has Louisville Metro in with 2-5" possible across Jefferson County. I think these amounts are a little high, and I'm leaning more toward the GFS forecast amounts (2nd map).
The 2nd map shows the GFS weather model, which is putting out 2-4" amounts over the northern half of the area, with 1-2" amounts south. I think this model is more in line with reality, and some of the melting that will occur with above freezing temperatures during part of this winter weather event.
The last map shows our forecast (which is not set in stone and subject to change). Basically we're looking at 2-4" amounts along and north of I-64, and 1-2" amounts over the southern half of the area. Notice our northern sections from Seymour to Madison, Indiana are very close to the higher amounts of 4-8". We're going to have to keep an eye out for the potential of some higher totals to the northeast of Louisville.
The biggest impact will be during the Wednesday morning commute when temperatures are near freezing. Roads will be slick and hazardous. Temperatures will go above freezing later in the morning, and road conditions will improve Wednesday afternoon. This is a here one day, gone the next event, with warming conditions for the rest of the week, with 60s this weekend!